Nanoliposomes meet folic acid: a precision delivery system for bleomycin in cancer treatment

HIGHLIGHTS

  • What: This study assesses the therapeutic potential of liposomal bleomycin (FL-BLM) against traditional forms in treating human ovarian carcinoma and oral Methods: FL-BLM was created using the thin film hydration technique with folic acid integration for active targeting. By comparing the therapeutic outcomes of FL-BLM with non-targeted liposomal bleomycin (L-BLM) and conventional bleomycin (BLM), the authors aim to demonstrate the benefits of folate-mediated targeting. Specifically, the authors assess the capability of FL-BLM to induce G2/M phase arrest a critical phase where cells can be halted before division, offering a . . .

     

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