Nanosystems based on sirna silencing hur expression counteract diabetic retinopathy in rat

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  • who: Marialaura Amadio from the Department of Drug Sciences, Section of Pharmacology, University of Pavia, Pavia, Italy have published the research: Nanosystems based on siRNA silencing HuR expression counteract diabetic retinopathy in rat, in the Journal: (JOURNAL)
  • what: The authors aimed to evaluate whether specifically and directly targeting HuR may represent a new therapeutic strategy to hinder VEGF overexpression. The authors loaded solid lipid nanoparticles (SLN) and liposomes loaded with siRNA silencing HuR expression, to assess their pharmacological profiles in a DR model. The major goal of clinical therapeutics is to provide and maintain effective . . .

     

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