No consistent antidepressant effects of deep brain stimulation of the bed nucleus of the stria terminalis

HIGHLIGHTS

• What: The aim of this study was to gather blinded data exploring the efficacy of applying DBS to the BNST in patients with highly refractory depression. Based on the literature supporting the role of the BNST in mood and anxiety disorders (for example, ) and the promising results of the pilot study , where the authors saw several patients with extremely treatment-resistant depression experience sustained periods of remission, the authors aimed to gather double-blind data to more robustly demonstrate the antidepressant potential of applying DBS to the BNST.
• Who: Paul B. Fitzgerald et al. from . . .
  

   

  

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