Peptostreptococcus anaerobius mediates anti-pd1 therapy resistance and exacerbates colorectal cancer via myeloid-derived suppressor cells in mice

HIGHLIGHTS

• What: The authors show that administration of P. anaerobius abolished the efficacy of anti-PD1 therapy in mouse models of CRC.
• Who: Yali Liu from the Mouse models The Animal Experimentation Ethics Committee of the Chinese University of Hong Kong approved all of the animal experiments conducted in this studyMice were kept in specific pathogen-free facilities, following a cycle of , h light and , h dark. Food and water were provided ad libitum. No statistical methods were used to pre-determine sample size but our sample sizes are similar to those in previous reports7. The . . .
  

   

  

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