Recent progress on vascular endothelial growth factor receptor inhibitors with dual targeting capabilities for tumor therapy

HIGHLIGHTS

  • who: Yun Liu from the (UNIVERSITY) have published the research: Recent progress on vascular endothelial growth factor receptor inhibitors with dual targeting capabilities for tumor therapy, in the Journal: (JOURNAL)
  • what: Perspective, the research progress of dualtarget VEGFR inhibitors is summarized, focusing on the rational targets selection, structure-activity relationships (SARs) and pharmacological activities of dual-target VEGFR inhibitors. This approach is characterized by integrating the potency of two selective inhibitors into a single molecule and is carried out by linking or merging the pivotal pharmacophores of selected maternal inhibitors.
  • how: As shown . . .

     

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