Siwu decoction mitigates radiation-induced immune senescence by attenuating hematopoietic damage

HIGHLIGHTS

• What: The authors made a mouse model of immune senescence with a single dose of 6.0 Gy 60Co γ-ray exposure (dose rate 102.63 cGy/min) to investigate the effects of IR on HSPCs, immune tissues and cells, and the effects of SWD on immune senescence mice. In this study, the telomeres of BM cells in the model group were found to be shortened compared to the control group, and SWD administration was shown to significantly inhibit this process, which suggested that SWD might play a role in anti-aging by preventing telomere shortening (Fig 7 . . .
  

   

  

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