Structure, activity regulation, and role of the mitochondrial calcium uniporter in health and disease

HIGHLIGHTS

  • who: Cristina Mammucari and Rosario Rizzuto from the Department of Biomedical Sciences, University of Padova, Padova, Italy have published the Article: Structure, Activity Regulation, and Role of the Mitochondrial Calcium Uniporter in Health and Disease, in the Journal: (JOURNAL)
  • what: This study analyzes the Pseudomonas aeruginosainduced inflammatory process that takes place in cystic fibrosis cells.
  • how: Studies were carried out in a transgenic mouse model expressing a DN-MCU .
  • future: Studies are required to clarify the expression profile of MCU components in a wider array of cancers.

SUMMARY

     

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