Synthesis and evaluation of pyridine-3-carboxamide analogs as effective agents against bacterial wilt in tomatoes

HIGHLIGHTS

• What: The authors report the synthesis of N-(4-phenylthiazol-2-yl) nicotinamide derivatives 4a-i by conjugating 2-amino-4-phenyl thiazoles with nicotinic acids, using the concept of pharmacophore hybridization to obtain compounds that comprise both thiazole and pyridine moieties. The evaluation of antimicrobial properties of synthesised compounds 4a-i against bacterial wilt pathogen This study shows that two active compounds have inhibitory effects on the bacterial wilt pathogen. The results of the experiment showed that tomato seedlings inoculated with R. solanacearum and treated with the 4a compound had a significantly increase in POX activity . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.