The protein arginine methyltransferase prmt9 attenuates mavs activation through arginine methylation

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• who: Xuemei Bai from the The Prmt9fl/fl mice were constructed by Cyagen using the CRISPR-Cas, gene-editing systemLyz2-Cre mice were obtained from Jackson Laboratory. Prmt9fl/fl mice were crossed with Lyz2-Cre mice to generate Prmt9fl/fl Lyz2-Cre mice. The Genotyping of Prmt9fl/fl was confirmed by means of PCR using the following primers, forward primer, `GGTTCTCTTCTTCCATCAAGTAG-3`, reverse primer, `-TCTTCCTTAAATACTTCCTCCGTG-3. The primers for Lyz2-Cre transgenic mice genotyping were o, mutant, `-CCCAGAAATGCCAGATTACG-3`, o, common, `-CTTGGGCTGCCAGAATTTCTC-3` and o, WT, `-TTACAGTCGGCCAGGCTGAC-3`. All the mice used in the present study were . . .
  

   

  

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