Vinpocetine alleviated alveolar epithelial cells injury in experimental pulmonary fibrosis by targeting ppar-γ/nlrp3/nf-κb and tgf-β1/smad2/3 pathways

HIGHLIGHTS

  • What: Mouse lung tissue was excised, cleansed, and cut | 14:11131 | 11 Vol.:(0123456789) | Vol:.(1234567890) 14:11131 | Vinpocetine inhibited TGF‑β1 induced fibroblasts to myofibroblasts differentiation through TGF‑β1/Smad pathway Given the anti-inflammatory and anti-fibrotic effect of VCN on pulmonary fibrosis, the study aimed to define the molecular mechanism underlying the role of VCN in BLM-induced fibrosis.
  • Who: Zeena A. Hussein from the Department of, College of Medicine, Al-Nahrain University, Baghdad, Iraq Department of have published the research work: Vinpocetine alleviated alveolar epithelial cells injury in experimental pulmonary fibrosis . . .

     

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