Wnt signaling contributes to the extrahepatic bile duct proliferative response to obstruction in mice

HIGHLIGHTS

• What: The authors focused on understanding the mechanisms regulating EHBD biology and the injury response.
• Who: Ashley N. Calder and colleagues from the DepartmentUniversity of Arbor, Michigan, USA have published the research work: WNT signaling contributes to the extrahepatic bile duct proliferative response to obstruction in mice, in the Journal: (JOURNAL)
• How: The authors used in_vivo mouse models transcriptomics morphometrics and in_vitro biliary models to define the WNT signaling landscape in the EHBD at homeostasis and in response to acute obstruction using a bile duct ligation (BDL) injury model.
• Future: This . . .
  

   

  

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