Circulating tumor dna (ctdna) dynamics predict early response to treatment in metastasized gastroesophageal cancer (mgec) after 2 weeks of systemic treatment

HIGHLIGHTS

• What: The authors aimed to test the prognostic impact of early dynamic changes in this novel biomarker and determine a cut-off for the prediction of treatment effects in restaging during the course of systemic chemotherapy for mGEC, which could eventually assist in early evaluation of response to treatment and allow for potential early changes in treatment in the future. This study was approved by the local ethics committee and informed consent was obtained from every patient included into the study prior to treatment initiation. A total of 13.5% of the study population underwent initial curative . . .
  

   

  

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