HIGHLIGHTS
- What: This study aims to identify key lncRNAs associated with 5-FU resistance in CRC using bioinformatic and experimental validation approaches. The authors seek to contribute to developing targeted therapeutic strategies to enhance CRC treatment. The authors observed significant overexpression of MALAT1 in the 5-FU-resistant sub-cell line compared to its parental cells, consistent with findings in different types of cancer.
- Who: Roxana Sahebnasagh and collaborators from the Department of Molecular Medicine, School of Advanced Technologies in Medicine, Tehran University of Medical have published the research: Review began 07/23/2024 Review ended . . .
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