HIGHLIGHTS
- who: Baptiste Saudemont from the (UNIVERSITY) have published the article: The fitness cost of mis-splicing is the main determinant of alternative splicing patterns, in the Journal: (JOURNAL)
- what: The authors propose a test to quantify the fraction of AS events corresponding to errors. The authors show that in both normal and in NMD-deficient cells AS rates strongly decrease with increasing expression level and with increasing number of introns.
- how: The authors therefore decided to define the canonical form as the one that is the most abundant in WT_cells (see Additional file . . .
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